Fluoride impairs the production of free radical scavengers such as glutathione. Fluoride impairs the function of enzymes that prevent lipid peroxidation. These enzymes include glutathione peroxidase, superoxide dismutase and catalase.
In an experiment with rats, fluoride impaired the growth rate, but the rats that were given beta-carotene and superoxide dismutase supplements had a faster growth rate. Fluoride causes damage to the fat in your body (lipid peroxidation), which is counteracted by the anti-oxidants beta-carotene and superoxide dismutase