"OXICELL represents a significant breakthrough in the field of natural medicine, particularly in the area of antioxidant supplementation. OXICELL is a metabolic cream that transports a stabilizedform of glutathione (GSH) and superoxide dismutase (SOD) into the bloodstream via transdermal liposomal delivery methods. The plasma markers of GSH and SOD are not raised when these are supplied orally; therefore, effective transport into the bloodstream via liposomaldelivery as found in OXICELL is preferential.1The transdermal method of delivery, known as liposomal delivery, is one in which lipid spheres called liposomes surround GSH and SOD, transporting it through the skin until it reaches the blood supply"
I think most are aware of SOD- Superoxide Dismutase. For wound healing...uv protection...Peyronies disease...and of course for hair. Tricomin and Folligen are two products that use cu peptides- which are SOD mimetics.
Glutathione...besides what the first link above says about it....frizz posted this at hairsite:
Glutathione, glutathione S-transferase and reactive oxygen species of
human scalp sebaceous glands in male pattern baldness.
Author
Giralt M; Cervello I; Nogues MR; Puerto AM; Ortin F; Argany N; Mallol J
Address
Unit of Pharmacology, School of Medicine, University "Rovira i Virgili,"
Reus, Spain.
Source
J Invest Dermatol, 1996 Aug, 107:2, 154-8
Abstract
We investigated the contribution of reactive oxygen species to the
development of sebaceous gland hyperplasia and the characteristics of the
glutathione S-transferase/glutathione system in male pattern baldness.
Glutathione S-transferase, glutathione,and thiobarbituric acid-reactive
substances were determined in sebaceous gland-enriched scalp skin of men
affected by male pattern baldness and were subjected to hair autotrans-
plantation. In comparison with the hairy occipital-donor areas,the following
results were obtained in alopecic frontoparietal samples: glutathione
S-transferase-specific activity increased 7-fold (p < 0.001); enzyme
affinity towards 1-chloro-2,4-dinitrobenzene decreased 2-fold (p = 0.009);
******glutathione content decreased 2.5-fold***** (p= 0.017); and thiobarbituric acid
reactive substances increased 2-fold (p = 0.006). Chromatofocusing analysis,
bromosulfophthalein IC50 values, enzyme-linked immunosorbent assay, and
immunohistochemistry with polyclonal antibodies raised against glutathione
S-transferases alpha, mu, and pi demonstrated the presence of alpha, pi,
and probably the 5.8 alpha isoenzymes in the sebaceous gland. These results
support the hypothesis that reactive oxygen species are involved in the
pathogenesis of sebaceous gland hyperplasia in male pattern baldness.
-----------------------------------------------------------------
nic's original post (which is what caught my eye back almost a YEAR ago!! (sept 26 2002 i posted on it on alt.baldspot)
---------------------------------
Post 1
------------------------------
more posts by nic which you should read:
------------
Post 2
Post 3
other posts:
Post 4
Post 5
Post 6
in this post he does say on points 3 & 4 that glutathione isnt stable and cant penetrate the cells...this might be the case but i wonder if liposomal glutathione would make any difference (im hoping uwbio or bug or larry david will answer)? im just trying to throw things out and perhaps someone can correct me if im wrong. there is a liposomal glutathione available.
