Interview with Gail Naughton, PhD, CEO, Chairman of the Board, Histogen

Discuss experimental or alternate treatments and products.

Moderator: moderators

Post Reply
User avatar
NegativeNorwood
Occasional Poster
Posts: 19
Joined: Thu Feb 11, 2010 1:45 am
Hair Loss Type: Androgenetic Alopecia (Male Pattern Baldness)
Norwood Level: Norwood III Vertex
Have you had a hair transplant?: Yes
Treatment Regimen: Dr Lee Xandrox plus, TB4, Lamas Serum, Revita, Lamas shampoo, Keto, 300 diode LLT, Elsom T1, T2

Interview with Gail Naughton, PhD, CEO, Chairman of the Board, Histogen

Post by NegativeNorwood »

What is the main responsible component of your solution
that appears to increase hair growth: wnt, other growth
factors, antioxidants…?

We believe that wnt proteins play an important role in the
hair regenerative properties of the conditioned medium. It is
known that wnt proteins are involved in both the initial in-
duction of the hair follicle and also in the regenerative phase
of the hair cycle. However, the formation and maintenance of
the hair is a complex process and many other proteins are
known to be involved. These include sonic hedgehog, activin,
and bone morphogenetic protein-2, which are involved in
a complex manner with the maintenance of stem cells and
the development of the cells into hair. The process also in-
volves inhibitors of these growth factors, such as follistatin,
which inhibits activin and is produced in large quantities by
fibroblasts in our manufacturing system.

They're definitely on to something, full interview found here - http://www.ishrs.org/PDF/F4-2009.pdf
User avatar
NegativeNorwood
Occasional Poster
Posts: 19
Joined: Thu Feb 11, 2010 1:45 am
Hair Loss Type: Androgenetic Alopecia (Male Pattern Baldness)
Norwood Level: Norwood III Vertex
Have you had a hair transplant?: Yes
Treatment Regimen: Dr Lee Xandrox plus, TB4, Lamas Serum, Revita, Lamas shampoo, Keto, 300 diode LLT, Elsom T1, T2

Re: Interview with Gail Naughton, PhD, CEO, Chairman of the Board, Histogen

Post by NegativeNorwood »

Follistatin supresses TGF -beta (code-name the hair follicle killer)

Fc fusion, human 50 µg can be found here: http://stemrd.com/index.php?/TGF-b-path ... e.tpl.html
Of course you could use curcumin as well.
intricate1
Prolific Poster
Posts: 424
Joined: Wed Apr 29, 2009 4:46 pm
Hair Loss Type: Androgenetic Alopecia (Male Pattern Baldness)
Norwood Level: Norwood II
Have you had a hair transplant?: No
Treatment Regimen: A&G hair complex rogain nizoral

Re: Interview with Gail Naughton, PhD, CEO, Chairman of the Board, Histogen

Post by intricate1 »

Do you mean curcumin topically or as a supplement?
Jacob
Prolific Poster
Posts: 3525
Joined: Fri Dec 12, 2003 9:38 am
Hair Loss Type: Don't Know
Have you had a hair transplant?: No

Re: Interview with Gail Naughton, PhD, CEO, Chairman of the Board, Histogen

Post by Jacob »

Hey NegativeNorwood..welcome to Hairlossfight..and great picture :lol:

Histogen definitely is something to look forward to.

I'd like to know the answer to intricate1's question as well :-s
User avatar
NegativeNorwood
Occasional Poster
Posts: 19
Joined: Thu Feb 11, 2010 1:45 am
Hair Loss Type: Androgenetic Alopecia (Male Pattern Baldness)
Norwood Level: Norwood III Vertex
Have you had a hair transplant?: Yes
Treatment Regimen: Dr Lee Xandrox plus, TB4, Lamas Serum, Revita, Lamas shampoo, Keto, 300 diode LLT, Elsom T1, T2

Re: Interview with Gail Naughton, PhD, CEO, Chairman of the Board, Histogen

Post by NegativeNorwood »

Hi Jacob and thanks for the welcome.
I should have been more specific, I was talking about ASCJ-9? the topical curcumin derivative formula, they said they're starting phase 2 trials and the end of 2009. Dunno whether I'd want to put that yellow paste all over my head though, I was thinking of getting Elsom to put it in a formulator for me. I'm not certain about supplementation and TGF beta levels, I had some info on it bookmarked somewhere. See if I can find it.
Post Reply