Capillogain® Tonic

[SyntheseLabRat]

@ChemicalBrother and @swissTemples

I read you both blow-dry your hair directly after the application of Capillogain Tonic.
Don´t do that, for the following reasons:

You likely "suck" the humidity out of your skin before the penetration process is completed. The penetration process isn´t already completed after everything got absorbed. The process continues inside the skin and it takes some time until the lower parts of the follicles and especially the dermal papilla is reached. If you blow the humidity out of your skin, penetration is disrupted too early and the active agents may get stuck in the upper parts of the skin. Also, if you blow-dry with heat you may activate TGF-beta in your skin which is usually bound in a complex in its latent form. And finally, heat isn´t great for some ingredients of Capillogain Tonic; for example the procyanidins are susceptible to heat.

Better use a towel in order to get rid of the stuff that sticks to your hair shafts.

[SyntheseLabRat]

@ChemicalBrother and @swissTemples

Take a look at this Consumer Medicine Information for Minoxidil:

http://www.chemistaustralia.com.au/prod ... ctId=28019

In the section "Things you must not do" it says, quote:

"Do not use a hair dryer on your head
to dry the Minoxidil solution."

[Joely]

Hi Joely, did you experience any sides or a shed?
I ask as I have had sides from Minox and Fin in the past, and while Minox worked for me, it came with a lot of baggage (ruined my skin & accelerated my balding when i stopped). With Fin, I had a bad experience - so again, sensitive to antiandrogens.
And being a NW-3 V, I can't afford a heavy shed.

Hi Aks20. I've experienced no sides or shedding since starting it. Again, must stress I have up until recently only been using it on my vertex so not had to use a massive amount of it per application. I have now started to use it on the hairline and touch wood no sides. Still far too early for me to comment on it's effectiveness but will keep update every now and again

[John Yossarian]

I tried using the product again and I didn't have any eye pain this time. I did get an extremely intense headache. Is that normal? I would like to try give the product a shot, but it seems I keep getting side-effects.

[SW2]

6 week update.. just started my third bottle (1st of the new batch).

last few weeks have been shedding more than usual.. no noticeable / visual regrowth.

will keep on it for at least 12 more weeks..

cheers glta!

[SyntheseLabRat]

I updated our testimonials section with new user reports and I translated the German reports:

http://www.functional-products.net/prod ... ain-tonic/

[SyntheseLabRat]

Since Capillogain is available also in the UK at amazon.co.uk now,
we offer our UK customers also a reduced price for a while:
£ 19.99 until 15.2.2013

http://www.amazon.co.uk/Capillogain%C2% ... 918&sr=8-1

[tinytim]

hi i noticed more frontal regression using cap combined with pimples on regressed site and hair follicles seem enlarged in this area so i have stipped using cap for a while any thoughts on this?

[SyntheseLabRat]

hi i noticed more frontal regression using cap combined with pimples on regressed site and hair follicles seem enlarged in this area so i have stipped using cap for a while any thoughts on this?

Sounds like an infection with bacteria. You should see a dermatologist, he may give you an antibiotic.
Do you have the pimples everywhere at the front or only on one side or only one spot?
You recently mentioned that you wanted to add something else to your regimen. What is it?

The Ethanol in Capillogain should help against the bacteria but since the phosphatidylcholine is food for them you may want to pause Capillogain until your infection is gone. You should see a dermatologist.

[KOJAK]

Hi SyntheseLabRat, I was wondering why Triaminodil is not written on my bottle list ingredients? ( It is from the second batch).
And also, why it is specified 2X /day whereas, it is written 1X/ day on the first batch ? Is it for a special reason ?
Don't take it badly, but it seems like you're unsure about it....

Thank you for your answer.


PS: Otherwise, 15 days on it and no sides yet. Dry pretty fast but leaves a very slight oily layer. But if you take it as an advantage, you can style your hair with it.

[SyntheseLabRat]

Hi SyntheseLabRat, I was wondering why Triaminodil is not written on my bottle list ingredients? ( It is from the second batch).
And also, why it is specified 2X /day whereas, it is written 1X/ day on the first batch ? Is it for a special reason ?
Don't take it badly, but it seems like you're unsure about it....

Thank you for your answer.


PS: Otherwise, 15 days on it and no sides yet. Dry pretty fast but leaves a very slight oily layer. But if you take it as an advantage, you can style your hair with it.

On the bottle the INCI names are listed. The INCI name of Triaminodil is PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE.

Once per day works. Some people used it 2 times per day and it worked too. However, so far it is not sure if 2 times daily works better than 1 application per day although it is likely the case. 2 times daily is an option for people to test if they get better results than with once daily. So in my opinion the test on the bottle should be "Apply 1 up to 2 times daily." Maybe I can convince my colleagues to change that. People who can´t incorporate a 2 times daily application in their daily routine can try go for the 1 times daily application.

[israelite]

weekly update!

[Jacob]

For the record..just started on my second bottle. I noticed some, including in the reviews, have commented on the smell. To me it smells a bit like mustard..or a gunpowder/mustard combo Nothing terrible..but I wonder if something like this would do much to "cover" the smell: http://www.amitech-usa.com/AMITECH%20PE ... T_Pres.pdf

NATICIDE is an effective, natural (vegetable-based)
broad spectrum preservative system used to control
microbial contaminants commonly encountered in
cosmetic formulation and application. Its broad
effectiveness allows NATICIDE to be used as the only
preservative in a formulation, thus enabling the
formulation to be termed ‘preservative free.’
NATICIDE is toxicologically mild and is defined as a
fragrance in both the U.S and Europe. NATICIDE has a
mild almond/vanilla odor and can be used as the primary
fragrance in a formulation.

is a natural (vegetable-based) preservative in liquid form
is effective against a broad range of gram-positive &
gram-negative bacteria, moulds, and yeasts
is defined as a fragrance (INCI and EINECS)
has a very low toxicological profile
is compatible with commonly used cosmetic ingredients
is easy to formulate with

can substitute for, or be used to enhance, the
primary fragrance.

[israelite]

For the record..just started on my second bottle. I noticed some, including in the reviews, have commented on the smell. To me it smells a bit like mustard..or a gunpowder/mustard combo Nothing terrible..but I wonder if something like this would do much to "cover" the smell: http://www.amitech-usa.com/AMITECH%20PE ... T_Pres.pdf

NATICIDE is an effective, natural (vegetable-based)
broad spectrum preservative system used to control
microbial contaminants commonly encountered in
cosmetic formulation and application. Its broad
effectiveness allows NATICIDE to be used as the only
preservative in a formulation, thus enabling the
formulation to be termed ‘preservative free.’
NATICIDE is toxicologically mild and is defined as a
fragrance in both the U.S and Europe. NATICIDE has a
mild almond/vanilla odor and can be used as the primary
fragrance in a formulation.

is a natural (vegetable-based) preservative in liquid form
is effective against a broad range of gram-positive &
gram-negative bacteria, moulds, and yeasts
is defined as a fragrance (INCI and EINECS)
has a very low toxicological profile
is compatible with commonly used cosmetic ingredients
is easy to formulate with

can substitute for, or be used to enhance, the
primary fragrance.

there was nothing wrong with the first batch! this is a problem in my eyes! why experiment ?

[Jacob]

What I posted there was just a preservative/fragrance that doesn't change the rest of the formula. Or are you referring to the second batch that's already out there now that Fred has already explained above...?

[israelite]

What I posted there was just a preservative/fragrance that doesn't change the rest of the formula. Or are you referring to the second batch that's already out there now that Fred has already explained above...?

Mine has a wonderful herbal smell. It was the first batch and it works great

[Jacob]

Ok..but there's now a new batch- I haven't tried it so don't know how it smells..but when you order next you'll be getting the newest formula..not the first batch.

I suppose things smell differently to different ppl..but I and a few others have pointed out that while it's not terrible..it's not exactly fit for daytime use. I just use it in the evening..and I'm fine with that. I've mentioned before that Elsom..which mega-loads things with herbals/actives..usually doesn't smell great either. But I'm still alive!

[israelite]

here is the best photo showing progress! small hairs are becoming patches of growth

[SyntheseLabRat]

Jacob

I agree, it is not fit for daytime use. At least if you get something stuck to your hair. The smell is less prominent if used only on bald spots like the temples where it can absorb without getting stuck to the hair shafts.

Thanks for the hint with the fragrance and preservative. I will take a look into it. It may be interesting for our Shampoo, too.
With respect to the Tonic, we don´t need an extra preservative and we are proud not to use any artificial preservative; we use only plain ethanol as preservative and some ingredients like Hinoki Oil help with the preservation.
We are also proud to not use any artificial fragrance but for a professional product used by many people it may be important to achieve a more pleasant smell. However, I am not sure if adding an artificial fragrance will solve the problem.

[Jacob]

That makes sense...he just uses his on the hairline.

And yeah..I didn't think yours needed a better or additional preservatives. Just that this one claims to be(and is even sold as) a fragrance as well...and is supposed to be natural. Maybe they'd send you a sample..

[afrothunder21]

I have a question for Synthese. For the hairs that are grown and are dependent on minoxidil, if you stop applying minoxidil and use capillogain, will those minoxidil dependent hairs shed?

Also, Capillogain grown hairs, if you stop applying Cap, will those hairs shed as well? Pretty sure they will but just wanna make sure...

[HairyHarry]

I keep having dry eyes / burning eye sensation. It really is a annoying problem. Therefore I am forced to quit cap. As I think it is the Triaminodil causing it - a lot of Minox-users also had the same issue - I look forward to the version without Triaminodil. Fred, any updates on that version?

[SyntheseLabRat]

I keep having dry eyes / burning eye sensation. It really is a annoying problem. Therefore I am forced to quit cap. As I think it is the Triaminodil causing it - a lot of Minox-users also had the same issue - I look forward to the version without Triaminodil. Fred, any updates on that version?

The version without Triaminodil will come but it will take a while.
Maybe your problem stems from the smell; molecules that get to your eyes through the air may irritate your eyes, especially if some stuff got stuck to your hairs.
You can try to apply Capillogain Tonic in the evening and wash your hair about 20 minutes after the application; that may help.

[SyntheseLabRat]

I have a question for Synthese. For the hairs that are grown and are dependent on minoxidil, if you stop applying minoxidil and use capillogain, will those minoxidil dependent hairs shed?

Also, Capillogain grown hairs, if you stop applying Cap, will those hairs shed as well? Pretty sure they will but just wanna make sure...

The term "shedding" is usually used for what I described in one of my earlier posts in this thread.
There are 3 possibilities:
1) It works less good for you than your Minox product: You won´t get what is usually called "shedding" (hair falls out synchronized) but you may observe a gradual slow decrease of your results.
2) It works better for you than your Minox product and may be able to activate the anagen phase for some hairs: You may experience the typical shedding but likely a mild version of it.
3) The effectiveness is about the same: You will observe no difference.

If you stop it, you will likely lose your results with time but likely not in an abrupt shedding. The anagen phase was activated for many hairs at about the same time and may have led to an initial shedding of hairs that were already in the telogen phase and got pushed out by the new hairs. But with time the hairs loose synchronization and fall out in a mosaic pattern since humans are no mice. So you will likely not observe a sudden shed but s slow gradual regression of your former results. However, we have no feedback on this scenario so far.

[John Yossarian]

SyntheseLabRat,

Have you looked into using Grateloupia elliptica in this product or any future products? It's a red seaweed that's been know to increase dermal papal cells, inhibit 5 alpha reductase, and also raises PGE2. I apologize if this has already been brought up in this thread, but I thought it was pretty interesting.

[prozium]

Hi,
I have just started to use capillogain. I can't report anything for the moment except that the color is very disturbing and the smell is from another age. You should try to optimize the appearence, it's important because Customers have the feeling to use some kind of experimental stuff without a lot of science in it. I will report if I keep using it.

[oppenheimer82]

SyntheseLabRat,

Have you looked into using Grateloupia elliptica in this product or any future products? It's a red seaweed that's been know to increase dermal papal cells, inhibit 5 alpha reductase, and also raises PGE2. I apologize if this has already been brought up in this thread, but I thought it was pretty interesting.

this. i agree with this guy, 100 %. you really need to incorporate this seaweed into your product. please contact the south korean scientists and ask them how they prepared their formula. this together with your nano encapsulation vehicle would make this product supreme. please do ii!

[SyntheseLabRat]

SyntheseLabRat,

Have you looked into using Grateloupia elliptica in this product or any future products? It's a red seaweed that's been know to increase dermal papal cells, inhibit 5 alpha reductase, and also raises PGE2. I apologize if this has already been brought up in this thread, but I thought it was pretty interesting.

I guess you are referring this publication:

http://pdf.medrang.co.kr/BT/2012/020/BT020-01-16.pdf

It sounds promising, however it is only an in vitro experiment, it shows only the potential but the proof is still missing. Hair growth is a complex matter. Although it is likely that this stuff works also in vivo, one has to be careful since it might have also negative effects on hair growth which may not show up in an in vitro experiment.
For example, Fucoidan is a constituent of some sea weeds. But only processed fractionized fucoidan works. The not fractionized stuff may even hurt. By cutting large molecules in pieces one can alter its action completely. An agonist can become an antagonist. The key that once opened the door because he fitted the key hole still fits the key hole but now doesn´t open it but clog it up.
So I am extra careful with these sea weeds and I would like to see in vivo experiments.
However, I will take a closer look into it.

[afrothunder21]

Synthese, does Capillogain block DHT? I think without a DHT blocker, hairloss will be inevitable eventually. I am currently using Lipogaine with great results but I am interested in trying Capillogain. I have read that I can use both but how does that work. Which product do I apply first and how long do I have to wait before I apply the other product.

[John Yossarian]

SyntheseLabRat,

Have you looked into using GP4G, which is extracted from sea plankton? Here's a link to the study:

http://www.ehrs.org/conferenceabstracts ... achgar.htm

[SyntheseLabRat]

Synthese, does Capillogain block DHT? I think without a DHT blocker, hairloss will be inevitable eventually. I am currently using Lipogaine with great results but I am interested in trying Capillogain. I have read that I can use both but how does that work. Which product do I apply first and how long do I have to wait before I apply the other product.

It contains some 5AR inhibitors.
Apply Capillogain Tonic first since it absorbs fast and with virtually no residue.
Wait about 20 minutes before you apply the other product.

[SyntheseLabRat]

SyntheseLabRat,

Have you looked into using GP4G, which is extracted from sea plankton? Here's a link to the study:

http://www.ehrs.org/conferenceabstracts ... achgar.htm

Thank you for the hint.
That is zoo plankton (consists of baby jellyfish and so on). I am not sure if that will be possible and I am not sure if you guys really want an extract from zoo plankton. I doubt the pure substance will be allowed for a cosmetic product.

[SyntheseLabRat]

I have to travel for a few days (4 or 5), therefore I may answer late.

[Hordini]

It looks like an interesting product that might thicken my hair and slow down my hairloss a bit until a real treatment ist available.

But I avoided Minox and Fin linke the plague in the past because my health is more important to me than my hair, so I won't buy cap with a Minox clone in it, no matter how small the dose is. I really hope the Minox free version will be available soon.

Another thing that worries me are the AR5 inhibitors - is there any chance that any of those will have systemic effects? Stuff like Ginseng, EGCG or GLA should be fine though, people take them orally for years (I took a GTE myself for some time) and reports of sides are anecdotal at best. No Fin-like horror stories anywhere on the net.

A "safety first" version without Minox and untested AR5 inhibitors would be nice.

[HairyHarry]

I agree!!!

[tinytim]

hi fred and others just been away from forum for a while and only just found out that the cap shampoo is available are all the products avail on amazon for uk now?is the shampoo good to use? i have come off finasteride as i really feel it does nothing for me so i have ordered some keratene retard as it lowers dht better than finast with two a day oral caps.
Just been to amazon uk and cap is £19.99 with free del but no shampoo there? also i note on fun products site you have to pay 11.90 euros postage so shampoo+cap combined works out at £54 uk which is a bit steep.

[israelite]

weekly update

[israelite]

another onnw

[tinytim]

Hi isr you are as said before using other products as well what do you think of the osteoscreen or psi proteosome which comes from ginkgo biloba flavanoids which some take as an oral for brain health did anyone know this.

[tinytim]

israelite i found out this interesting info from hair loss research a 73 year old man slick bald for 45yrs regrows a full head of hair on oral spironolactone which points out that hair follicles never die? he was not taking it for hair loss it was for liver cirrhosis as we know oral spriro is toxic for us and can cause breast enlargement and people take it in gender realinement which we do not want the point here is that as said we can regenerate new growth on our slick bald areas but what do we use im hoping that the new oral keratene retard may do this without side affects.
Going back to spiro i wonder if there is a safe oral dose without sides i think i will use topical spiro with the retard oral,i really do not think that capillogain will do anything as wonderful as that 73 year old man had.

[KOJAK]

Ok quite point on the situation :
- One month treatment.
- shedding seems to decrease.
- Hairline has receded and overall looks sliglty worth than before.
Hope next month will be better...

[MG63]

I've switched from Spectral DNC and noticed some shed.

I do have a question - what is the minimal time the Capillogain can be left on the scalp?

[Norwood]

Hi guys. New to the forum. I have just started treating my thinning hair after a long break from minox and propecia. I've recently ordered Capillogain and will use it along with minox and nizoral. I may even start propecia again but in smaller doses as it was the side effects that bothered me. Going to mix it in with minox and apply topically then maybe add 0.5mg daily by mouth. I was going to use trx2 but the reviews aren't great and for the same money I can get a lot more and if the reviews change I will consider adding it. Any advice much appreciated. I'm 30 with a NW of 2.5

[HairyHarry]

Is someone using the Capillogain Shampoo? If so, do you like it?

[SyntheseLabRat]

hi fred and others just been away from forum for a while and only just found out that the cap shampoo is available are all the products avail on amazon for uk now?is the shampoo good to use? i have come off finasteride as i really feel it does nothing for me so i have ordered some keratene retard as it lowers dht better than finast with two a day oral caps.
Just been to amazon uk and cap is £19.99 with free del but no shampoo there? also i note on fun products site you have to pay 11.90 euros postage so shampoo+cap combined works out at £54 uk which is a bit steep.

The Shampoo should be available at amazon soon. I don´t know why it takes so long.

Which "fun page" are you talking about?

For a short time somebody (not us) tried to sell Capillogain Tonic for 113.80$ at amazon.com.
And Spectral is using Triaminodil now, too.

Well, no comment ...

[SyntheseLabRat]

I've switched from Spectral DNC and noticed some shed.

I do have a question - what is the minimal time the Capillogain can be left on the scalp?

Try to leave it on for at least 20 minutes before you shower.

[Jacob]

To be fair to Elsom..they have offered raspberry ketone for quite some time. In a finished product- http://www.skin-scalp.com/ or by request. I remember a bcapop(sp?) even looking to have them do a custom shampoo with it way back...but for some reason it never materialized.

I've always assumed someone from Spectral was reading these forums..starting from the beginning. But then again I always wondered if they were Lipoxidil that changed their name and went viral...since they were using so many "new" things etc.

[SyntheseLabRat]

To be fair to Elsom..they have offered raspberry ketone for quite some time. In a finished product- http://www.skin-scalp.com/ or by request. I remember a bcapop(sp?) even looking to have them do a custom shampoo with it way back...but for some reason it never materialized.

I've always assumed someone from Spectral was reading these forums..starting from the beginning. But then again I always wondered if they were Lipoxidil that changed their name and went viral...since they were using so many "new" things etc.

Well, you are too fast for me Jacob, I already wanted to edit my post.

[Jacob]

They call me Lightning J

[Aks20]

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