Vitamin E may reverse male pattern baldness: Study

[goten574]

I'm sure I am seeing some regrowth or at least thickening of the hair, but I don't know if it's the toco doing this or the other stuff I am taking. Could be the MSM, the green tea, the spearmint tea, the oils kicking in, the other supplements I take, the balayam... who knows!

[helpmyhair]

Lets get some more updates from Toco users.

[Jacob]

I'm taking 'em..but can't say if it's doing anything.

[intricate1]

This patent claims priority from the patent applications of the same name, one of which was filed in Malaysia on May 22, 2002 and assigned Malaysian patent application number PI20021894, and the other which was filed in the United States on May 17, 2003 and assigned U.S. patent application Ser. No. 10/440,564. The present application is a continuation of application Ser. No. 10/440,564, filed May 17, 2003, now abandoned.

Claims:
The invention claimed is:

1. A method of promoting hair growth and reducing hair loss in a mammal in need thereof consisting of administering to said mammal a composition consisting of mixed tocotrienols, alpha-tocopherol and a pharmaceutically acceptable excipient, wherein the minimum concentration of said mixed tocotrienols is about 0.1%, and wherein said composition is administered in the form of an oral dosage.

2. The method of claim 1, wherein said mixed tocotrienols are a mixture of α-, γ-, and δ- tocotrienols.

3. The method of claim 1, wherein said oral dosage is in the form of a soft gelatin capsule.

4. The method of claim 1, wherein an oral administration of said composition is at a dosage of about 20 mg–1500 mg per day.

5. A method for promoting hair growth and reducing hair loss consisting of administering to a mammal in need thereof a pharmaceutically acceptable excipient, alpha-tocopherol and a tocotrienol selected from the group consisting of α-, γ-, and δ- tocotrienols, wherein the: minimum concentration of said tocotrienol is about 0.1% , and wherein said pharmaceutically acceptable excipient, said alpha-tocopherol and said tocotrienol are administered in the form of an oral dosage.

6. The method of claim 5, wherein the amount of said tocotrienols is about 50 mg.

7. The method of claim 5, wherein said oral dosage is in the form of a soft gelatin capsule.

8. The method of claim 5, wherein an oral administration of said composition is at a dosage of about 20 mg –1500 mg per day.

Description:
TECHNICAL FIELD OF THE INVENTION
The present invention generally relates to a hair growth formulation, in particular to a formulation comprising tocotrienol for promoting hair growth.

BACKGROUND OF THE INVENTION
Hair loss or alopecia is a common problem in both males and females regardless of their age. There are several types of hair loss, such as androgenetic alopecia, alopecia greata, telogen effluvium, hair loss due to systemic medical problems, e.g., thyroid disease, adverse drug effects and nutritional deficiency states as well as hair loss due to scalp or hair trauma, discoid lupus erythematosus, lichen planus and structural shaft abnormalities. (Hogan and Chamberlain, 2000). Of the above, androgenetic alopecia is the most common cause of hair loss, affecting about 30% of individuals who have a strong family history of hair loss. (Bergfeld, 1988). Androgenetic alopecia is caused by three interdependent factors: male hormone dihydrotestosterone (DHT), genetic disposition and advancing age. DHT causes hair follicles to degrade and further shrink in size, resulting in weak hairs. DHT also shortens the anagen phase of the hair follicle growing cycle. Over time, more hairs are shed and hairs become thinner. Possible options for the treatment of alopecia include reassurance, hair prosthesis, surgery and topical/oral medications. (Hogan & Chamberlain, 2000; Bertolino, 1993; Setty, 1970).

The most common pharmacological management of androgenetic alopecia is topical minoxidil and finasteride taken orally. The main problem with topical minoxidil therapy is patient compliance, although it has been shown to be effective in a few studies. (DeVillez et al, 1994; Trancik R J, 1998). On the other hand, oral finasteride is associated with significant adverse effects such as decreased libido, impotence and ejaculation disorders. (Chen et al, 1996).

In addition, there is a report by Goldman et al. (1996) which evaluates whether male pattern baldness is associated with a deficiency in oxygen supply to body tissue. The results indicate that penetration of oxygen was lower in the bald frontal scalp than in hair-bearing temporal scalp area. As such, good blood supply to the scalp is essential to maintain normal cycle of hair growth.

Tocotrienol, a form of vitamin E, is a potent anti-oxidant and has been found useful in combating many health problems. While there was a report of the beneficial effects of vitamin E in hair care products (Shipp, 1994), its potential in the restoration of hair in patients taking tocotrienols as a supplement has yet to be explored. Thus, the aim of the present study was to investigate the possible intervention effects on hair loss with tocotrienols.

Vitamin E consists of 8 molecules or isoforms; four of which are known as tocopherols and four of which are known as tocotrienols. Structurally, both consist of a chromanol head and a phytyl side chain. The difference between tocopherols and tocotrienols lies in the phytyl side chain. Whereas the phytyl side chain of tocopherols is fully saturated, that of the tocotrienols has three double bonds at the 3, 7 and 11 positions. Both tocopherols and tocotrienols are further designated as alpha-, beta-, gamma- and delta-isoforms depending on the number and position of the methyl groups on the chromanol ring. Thus, tocopherols and tocotrienols are distinctively different and are not derivatives of each other (Theriault et al, Clinical Biochemistry (1990) 32(5):309).

Because of the difference observed in the phytyl chain of tocopherols and tocotrienols, the two series have also been reported to possess differences in biological activities, with the tocotrienols reportedly to be superior (Qureshi et al, J Biol Chem (1986) 261:10544; Serbinova et al, Free Radic Biol Med (1991) 10:263). Moreover, the half life of tocopherols in humans has been reported to be about 20 hours while the half-life of tocotrienols was reported to be between 2–4 hours only.

Although tocopherols have been mentioned in other patents describing hair growing agents, tocopherols are not the major active ingredient but merely act as formulation aid, as mentioned in some of the patents. The patent by Kamimura (European Patent Application Number EP1232740A2) relates to a hair growing agent, comprising phosphatidic acid as an active ingredient (as claim 1). Only in the subsequent claims did the inventor mention that “A hair-growing agent comprising, as active ingredients, the phosphatidic acid, and one or more members selected from the group consisting of proanthocyanidin, tocopherol, derivatives of tocopherol, panthothenic acid . . . ”. Moreover, the above patent only mentioned tocopherol as one of the components of the invention and not tocotrienols per se. It should be emphasized that tocotrienols are distinctly different from tocopherols.

In the patent by Mitsuyama (JP2000038340), it relates to peroral hair growth stimulants containing minoxidil AND one or more compounds chosen from a group of molecules which may consist of vitamin E. The emphasis was on minoxidil and not Vitamin E although Vitamin E as a group encompasses both tocopherol and tocotrienols. Tocotrienols were not being mentioned at all for preventing hair loss as the sole active ingredient but instead vitamin E was used more as a supplement to minoxidil or as an excipient in the preparation. On the other hand, the present invention specifically relates to preparations containing tocotrienols for promoting hair growth and not in combination with other molecules.

U.S. Pat. No. 4,439,432 (Peat) relates to the use of progesterone solubilized in tocopherol for the correction of progesteron deficiency states. The tocopherol in the preparation was not indicated for the treatment of any ailments listed in the patent, which include abnormal hair growth resulting from androgen excess, but rather the tocopherol was used as a non-toxic solvent to solubilize the progesteron such that it did not crystallize out upon mixing with biological fluids. The tocopherol used in the U.S. Pat. No. 4,439,432 was not meant to exert any therapeutic action. Tocopherol in this case was used solely as an inert excipient/carrier for progesterone so that the progesterone would not crystallize out as in the case of a prior art where ethanol was used. U.S. Pat. No. 5,591,772 by Lane et al. relates to the use of novel tocotrienols and tocotrienol-like compounds as hypocholesterolemic, antithrombotic, antioxidizing, antiatherogenic, anti-inflammatory and immunoregulatory agents. It was never mentioned in the patent that tocotrienols could be used for promoting hair growth or preventing hair loss as stated in the present invention. Hence, the aim of the present study was to investigate the possible intervention effects on hair loss with tocotrienols.

BRIEF SUMMARY OF THE INVENTION
Accordingly, it is the primary objective of the present invention to provide a mixed tocotrienols composition. It is also another objective to provide a formulation for promoting hair growth and preventing hair loss using the mixed tocotrienols of the present invention.

This and other objectives of the present invention are accomplished by: (1) a mixed tocotrienols composition; (2) a formulation for promoting hair growth and preventing hair loss in a mammal wherein mixed tocotrienols are combined with a pharmaceutically acceptable excipient; (3) a formulation for promoting hair growth and preventing hair loss in a mammal wherein α-, or γ-, or δ- tocotrienols is combined with pharmaceutically acceptable excipient; and (4) the use of a formulation as claimed in the present invention for promoting hair growth and preventing hair loss in a mammal.

The formulation according to the present invention, when administered orally or topically, promotes hair growth and prevents hair loss, and the number of hairs appears to increase in those persons experiencing hair loss.

BRIEF DESCRIPTION OF THE DRAWING
Other aspects of the present invention and their advantages will be discerned after studying the Detailed Description in conjunction with the accompanying figure in which are provided for illustrative but not limiting purposes:

FIG. 1 shows the effect of the tocotrienol formulation according to the present invention on the mean number of hairs of volunteers after supplementation for 5 months.

DETAILED DESCRIPTION OF THE INVENTION
Effect Of Tocotrienol Supplementation On Hair Growth

Study Design

A randomized, double blind, placebo-controlled two groups parallel study was conducted to compare the effect of a mixture of tocotrienols, comprising α-, γ-, and δ-tocotrienols and alpha-tocopherol, with placebo on hair growth. All volunteers were randomized to receive one capsule comprising either (i) a mixture of tocotrienols and alpha-tocopheral, or (ii) a placebo, twice daily after food over a period of at least 5 months. They were seen for an efficacy evaluation every month throughout the study. The control was a placebo capsule containing 600 mg of soya bean oil, and the tocotrienol formulation consisted of capsules containing a mixture of about 50 mg of tocotrienols and about 23 i.u. alpha-tocopherol. The entire study took 15 months for completion.

Although the preferred embodiment of the formulation is in the form of soft gelatin capsule, other oral pharmaceutical dosage forms are not excluded. The preferred dosage range of tocotrienols for oral consumption is from about 20 mg to about 1500 mg/day. The formulation may also be applied topically and may be in the form of a cream, a lotion, an ointment, a gel, a liquid, or any other topical form. The concentration of tocotrienols used in the topical formulation is about 1.0%, and the minimum concentration of tocotrienols in any formulation is about 0.1%.

Inclusion Criteria

Volunteers of 15 years of age or older and in good general health were recruited into the study. Alopecia must have present for least 2 months and the areas alopecia must not have any visual evidence of new hair growth. Volunteers previously exposed to minoxidil were ineligible to participate in the study, as were patients who have used hair-restorers or systemic drugs like steroids, antihypertensives, cytotoxic compounds, vasodilators, anticonvulsant drugs, β-blockers, spironolactone, cimetidine, ketoconazole, estrogens or progesterons within the previous three months. Patients experiencing hair loss due to thyroid disease, adverse drug reactions, scalp or hair trauma, structural hair shaft abnormalities and lichen planus were excluded from the study.

Efficacy Evaluation

Two parameters were chosen to evaluate the efficacy of tocotrienols and alpha-tocopherol supplementation:

i) Hair count—hair count served as the primary efficacy measure. An area of 2×2 cm was selected in the area of hair thinning for each patient, and the two opposing corners of the square were permanently marked (using a 4 cm 2 wire template) to ensure that the hair in the same area was counted at each visit.
ii) Weight of hair—a small tuft of hair (at least 20 strands) within the demarcated area was clipped horizontally. Twenty strands were randomly chosen and cut into 1 cm in length. The total weight was obtained using a microbalance and the mean weight was recorded.
All of the two parameters were obtained at baseline and every month thereafter during the study. Only the terminal hair growth was recorded and analyzed.

Results of Hair Growth Studies

Nineteen patients (14 men and 5 women) entered the study and completed at least the first 5 months of therapy. Their ages ranged from 23 to 59 years. The mean duration of current alopecia episode was approximately 5 years. The extent of alopecia was as follows: less than 25%, 6 patients; 25–49%, 8 patients; 50–74%, 4 patients; 75–99%, 1 patient.

Eleven volunteers were randomized to receive the tocotrienol formulation supplementation while 8 volunteers were in the placebo group. Comparability of the treatment groups with respect to initial hair counts as well as the weight of hair was assessed. No statistically significant difference between treatment groups was detected for any of the above characteristics.

At the end of the supplementation period, all volunteers in the tocotrienol formulation group had positive results, recording an increase in the number of hairs in the evaluation area. Seven volunteers (64%) showed regrowth of between 10–35% while 3 volunteers (27%) had 50% or greater regrowth. One volunteer had regrowth of more than 100%. The mean percentage of increase in the number of hairs is 42.4±40.9% (mean±SD). (Table 1 and FIG. 1). The increase is statistically significant (p<0.05) when analyzed using paired sample t-test. On the other hand, of the total eight volunteers in the placebo group, two showed hair regrowth, two had hair loss while the other four did not show any significant changes in the number of hairs. The mean percentage of increase was 1.4±13.8%. No statistically significant difference (p>0.05) in the number of hairs was detected between baseline and post-supplementation, thus indicating that the placebo effect did not occur during this study.

However, in terms of the weight of the hair, no statistically significant difference (p>0.05) between pre- and post-supplementation was detected for both groups of volunteers (tocotrienol and placebo). The mean percentage of weight increment was 16.4±42.5% in the tocotrienol formulation group while that of the placebo group had an increase of 5.7±40.1%. (Table 2).

The above-mentioned studies therefore indicate that supplementation with a formulation comprising a mixture of tocotrienol, alpha-tocopherol and pharmaceutically acceptable excipient appears to promote hair growth and increase the number of hair in persons experiencing hair loss. The choice of pharmaceutically acceptable excipients will be obvious to those skilled in the relevant art. Acceptable excipients include any inert, compatible substances added to make the final dosage forms, for the formulations, such as tablets, capsules, or soft gelatin capsules. For example, vegetable oil can be added as an excipient to make up the volume for the encapsulation of soft gelatin capsules. As such, a pharmaceutically acceptable excipient includes any excipients that are approved for use by the relevant authorities and are compatible with tocotrienols.

TABLE 1
Individual number of hair at baseline and 5 months
after tocotrienol and placebo supplementation
Tocotrienol Placebo
Volunteer Baseline 5 months % change Volunteer Baseline 5 months % change
1 290 477 64.5 1 194 244 25.8
2 380 463 21.8 2 391 385 −1.5
3 496 603 21.6 3 358 369 3.1
4 223 370 65.9 4 354 296 −16.4
5 110 133 20.9 5 223 258 15.7
6 266 358 34.6 6 286 267 −6.6
7 110 274 149.1 7 307 275 −10.4
8 258 298 15.5 8 219 223 1.8
9 314 344 9.6
10 287 316 10.1
11 179 274 53.1
Mean 264.8 355.5 42.4 Mean 291.5 289.6 1.4
SD 112.9 124.7 40.9 SD 73.6 58.2 13.8
TABLE 2
Individual weight of hair (g) at baseline and 5 months
after tocotrienol and placebo supplementation.
Tocotrienol Placebo
Volunteer Baseline 5 months % change Volunteer Baseline 5 months % change
1 0.0920 0.1078 17.2 1 0.2280 0.1200 −47.4
2 0.0970 0.0962 −0.8 2 0.0915 0.0945 3.3
3 0.2490 0.2480 −0.4 3 0.1974 0.1956 −0.9
4 0.0732 0.1552 112.0 4 0.0822 0.1587 93.1
5 0.1055 0.0849 −19.5 5 0.1899 0.1789 −5.8
6 0.1315 0.1577 19.9 6 0.1158 0.1206 4.1
7 0.1094 0.1295 18.4 7 0.1398 0.1625 16.2
8 0.1405 0.1686 20.0 8 0.1187 0.0988 −16.8
9 0.1284 0.0837 −34.8
10 0.1380 0.2348 70.1
11 0.1692 0.1317 −22.2
Mean 0.1 0.1 16.4 Mean 0.1 0.1 5.7
SD 0.0 0.1 42.5 SD 0.1 0.0 40.1
REFERENCES
Bergfeld W F (1995). Androgenetic alopecia: an autosomal dominant disorder. Am J Med 98:95S–98S.
Bertolino A P (1993). Clinical hair loss: diagnosis and treatment. J Dermatol 20:604–610.
Chen W. Zouboulis and Cafanos C E (1996). The 5-alpha reductase system and its inhibitors. Dermatology 193:177–184.
DeVillez R L, Jacobs J P, Szpunar C A & Warner M L (1994). Androgenetic alopecia in the female. Treatment with 5% topical minoxidil solution. Arch Dermatol 130:303–307.
Goldman B E, Fisher D M and Ringler S L (1996). Transcutaneous PO2 of the scalp in male pattern baldness: a new piece to puzzle. Plast Reconstr Surg 97(6):1109–1116.
Hogan D J and Chamberlain M (2000). Male pattern baldness. South Med J 93(7):657–662.
Shipp J J (1994). Hair care products. In: Chemistry and technology of the cosmetics and toiletries industry . (Williams DF and Schmitt WH, ed.s), p 66. Blackie Academic & Professional: UK.
Setty L R (1970). Hair pattern of the scalp of white and Negro males. Am J. Phys Anthropol 33:40–55.
Trancik R J (1998). Update on topical minoxidil in hair loss. Annual Meeting of American Academy of Dermatology, Orlando.
While the preferred embodiment of the present invention has been described, it should be understood that various changes, adaptations and modifications may be made thereto. It should be understood, therefore, that the invention is not limited to details of the illustrated invention shown in the figure and tables, and that variations in such minor details will be apparent to one skilled in the art.
What I don't like is the change in the weight of the hair buy everything is all good

[Lapwing]

I just started taking Toco-8 last week so hopefully I will have something good to report in December.

[SW2]

Do you guys take two (2) Tocomin SupraBio Palm Tocotrienol Complex -- 60 mg pills at once or one in the morning and one at night?! I believe 100mg's were used in the study, right?

thanks!

[Jacob]

I take two different products..the tocopherols I take in the a.m...the tocotrienols I take in the evening(as suggested by the company).

[SW2]

By 'the company' do you mean Carotech as in there study or by someone else? Do you think results will be dependant on taking pherol's and phenols at different times?

[Jacob]

NEEDs.....AC Grace and others. I don't know if it was discussed here in this thread..it's quicker doing a search on what was discussed at Hairsite: http://www.hairsite.com/hair-loss/forum ... nswer.html A bit of a correction on some of that in that thread..I think we learned the "SupraBio" product does contain the tocopherols as well(in that hair loss study)..or am I thinking of another product...

Who knows if it makes it better hair-wise..I'm just taking them the way it makes the most sense

[himinal]

Week 7: Shedding significantly down (from 100 hairs a day to 10-15 hairs a day), no real regrowth
Week 11: Shedding still down (10-15 hairs a day), a couple dozen new hairs on the crown
Week 14: Shedding picks up a little (25-30 hairs a day), additional slight regrowth on crown
Week 16: Uptick in shedding (30-40 hairs a day); no new regrowth, but most of the previous "new" hairs seem to be doing pretty well

Just to compare to goten574's results, I've definitely not seen an increase in body hair or any sort of hair thickening.

[Lapwing]

I been on Toco-8 for about 3 weeks now. I can't report on hair yet, but I feel I have a little more energy and increased libido since I added Toco 8.

[helpmyhair]

more updates please guys?

[clydro]

I just started toco-8 so I'll keep everyone posted on the results. Is anyone seeing any positive results so far?

[Jacob]

Another plus:

Gamma Tocotrienol Assists Bone Strength

A new study shows that vitamin E, and in particular the form known as gamma tocotrienol, helps build stronger bones with better biomechanical strength.

The authors concluded, “Vitamin E supplementation, especially with the gamma isomer, improves bone structure, which contributed to stronger bone. Therefore, vitamin E has the potential to be used as an anabolic agent to treat osteoporosis or as bone supplements for young adults to prevent osteoporosis in later years.”

This new study goes along with three earlier studies lending support to the tocotrienol form of vitamin E as a superior bone support nutrient. The earlier studies showed that tocotrienols reduce inflammation in bone that leads to bone loss, can offset the harmful effects of steroid use on bones, and assist in the process of normal bone calcification.

While tocotrienols are often used for cardiovascular and brain health, here we see that they are yet another wonderful nutrient for bone health.

[intricate1]

Some of you guys have been taking this for a while now ANY feedback? For me is only a month

[goten574]

I am seeing regrowth (or what appears to be regrowth... could just be thickening) but visually the back of my head looks better and the little bald spot is filling in. No changes to the front of my hair (or if there is, it's very minor) and I cannot say if the tocos are the reason for this as I also am trying Balayam. I know I am seeing improvement though, it really is not in my mind.

I know I said no chances to the fron of my hair but when I wet it, I don't see as much scalp as I use to...

[intricate1]

Gotten how long has it been

[goten574]

I started in mid - late August.

[helpmyhair]

Lets get some updates from the Tocotrienol users!

I've been using AOR brand that contain 125mgs, but only a few weeks now, so nothing to report.

Though I am starting to think this may be a scam.. The study was conducted by Carotech.. and other one I could find was by Toco-8.. its seems as though these two companies are trying to push their products to get people to buy it.. and the studies seem too good to be true.. is there anyone that is actually getting real regrowth from this?

[OMGmyhair]

I've been on Vit-E for about a month now. I take 1 Swanson Vit-E with toco.

It's sort of hard to tell if it's working because I shaved my head (0-guard) about a month and a half ago. At that point, I also started 7+ daily vitamin plan, and recently Elsom T1 + T2.

What I can say is that now that my hair has regrown about an inch and when I run my hands from the back of my head to the front over a sink, I get almost no shedding at all (1 -5 hairs max).

Not sure if it's because I shaved my head, taking vitamins, or from T1 + T2.

[chain]

Hello Guys,

Does someone of you have a discount coupon for Swanson that can share with me. I am planning to make another order from the Vitamin E with Tocotrienols. Thank you in advance.

[Jacob]

Always check places like this http://www.retailmenot.com/view/swansonvitamins.com or just do a google search for "Swanson"(or any other company) and "coupon".

If it works..the latest one mentioned there is YES1103 for 10% off.

[Jacob]

Some other products/sources..and news on tocotrienols:

http://www.iherb.com/Allergy-Research-G ... 11172?at=0

http://www.iherb.com/Doctor-s-Best-Best ... 17131?at=0

http://www.vrp.com/ProductPage.aspx?ProdID=3090&zType=1

Toco/krill oil/resv combo:
http://www.rockwellnutrition.com/assets ... lsplus.pdf

Another combo:
http://www.rockwellnutrition.com/Lipotr ... _1703.html

[Jacob]

Swanson now has coq10/tocotrienol combos. From 100mg to 600mg of coq10..and 20-60mg of tocotrienols.

http://www.swansonvitamins.com/SWU349/ItemDetail?n=

[himinal]

Week 7: Shedding significantly down (from 100 hairs a day to 10-15 hairs a day), no real regrowth
Week 11: Shedding still down (10-15 hairs a day), a couple dozen new hairs on the crown
Week 14: Shedding picks up a little (25-30 hairs a day), additional slight regrowth on crown
Week 16: Uptick in shedding (30-40 hairs a day); no new regrowth, but most of the previous "new" hairs seem to be doing pretty well
Week 24: My crown hasn't had any additional improvements over the past 2.5 months, but it has maintained nicely. I've also had a slight increase in chest and arm hair. That's the good news. The bad news is that over the past 8 weeks, my hairline has taken a severe hit. If I had to estimate, I'd say I've lost about 20% of the hair on the front region of my head.

[clydro]

himinal, are you going to continue taking the toco-sorb?

[intricate1]

I don't think tocos are doing anything for me I just take them for the health benefits

[himinal]

himinal, are you going to continue taking the toco-sorb?

I have a two month supply left, and I do imagine I'll continue beyond that.

[davetherave]

Bumping this up.

Anyone having results?

[goten574]

I can't say it's doing much, depends what day it is lol

[intricate1]

Taking this everyday for 5 months now and can't say I have seen any regrowth yet. I take the expensive unique brand which costs 40 dollars abottle and it lasts 2 months. I am also using dermaheal longer than that and it has only helped me maintain. I should note that I take msm fish oil vitamins reserv/curcum also. I don't know if any of the supplements realy have helped with hair. I do like taking supps so maybe I will continue fir other benefits.

[iluvhair]

himinal -

any update?

your story of the hairline getting worse, makes me think it could be the fact that vitamin e is known to raise testosterone, and i beleive the hairline is more sensitive to testosterone than the crown.

im eager to hear if your hairline got better, if you stayed on vit e, or what happenned.

cheers!

[j872]

So which is the best bang for buck?

[goten574]

Been taking Swanson Tocorienols since August 2009 and cannot notice much change (if any). I take between 75mg - 150mg a day

[sarmelly]

Is Omega 3 really that important in pregnancy? I read that I need to consume DHA's or Omega 3's during the final trimester but its only found in foods that I hate, like salmon! Is it really that important? I bought some eggs that have omega 3 in them today even though they were a bit too expensive for my budget, will they do just as well?

[Brunz19]

Is Omega 3 really that important in pregnancy? I read that I need to consume DHA's or Omega 3's during the final trimester but its only found in foods that I hate, like salmon! Is it really that important? I bought some eggs that have omega 3 in them today even though they were a bit too expensive for my budget, will they do just as well?

You can get Omega 3 6 9 soft gel caps from pretty much any natural health store. I've even started taking some just this week.

[Jocko59]

Wow, that's an embarrassing shameless plug. You wouldn't happen to work for that site would you? LOL

[Jacob]

Well he did start out here by saying he sold those things..so as long as it's out in the open.

[johnsp]

There is nothing shameless when something actually works. It does frustrate the hell out of me when people or companies claim a major breakthrough and it fails just like the majority of hair loss cures. Many companies using false images and photoshop to present falsified results. Other so called hair loss professionals who are only trainned in sales and focus on convincing people the only thing they can do is to stick a toupee on there head. Or, MD's perscribing drugs to young men that are going to have negative life long effects on not only them but their unborn children too. Usually with minimal results but great kick backs from drug companies for the perscribing practitioners. I will not go on any more.
Thank you Jacob, I am always upfront. It frustrates me as well that true LLLT is rarely used in regard to hair loss, many machines are either too low in Mw or Nm, many hand helds are nothing more than LED's. LLLT was originally used to regrow, repair and rejuvinate tissue and bone, that is what happens to the scalp.
Not wanting to offend any members, I just want to get the truth out there about what will and does work.
I personally have treated 4 clients with cicatricial alopecia (arguably the worst form of hair loss) sucessfully using anti-microbial solutions, all these clients are now enjoying their freedom. One of these clients actually use to cut his scalp with a razor. The research foundation would not listen to me as they still had 4 years of research money to acquire. This frustrates me, at the expense of Mr Joe Public.

[intricate1]

is anyone taking this still? for health or hair?

[Joey Ramone]

Please hijacking threads, johnsp.

[intricate1]

I just bought two month supply... I thinks this really helps with overall health and skin... Maybe even with her lol

[goten574]

I ran out of Tocos late August and although I didn't see any noticeable regrowth, I think it may have helped slow hair loss down. Since stopping, I have noticed more shedding. I was on 75mg-140mg Tocotrienols daily for a year (usually just 75mg). I am not sure if I should buy more, at the moment, I think not.

[intricate1]

My skin has no blemishes, and if something makes my skin like this then taking it internally should be good for hair. I like the unique brand... I also do feel it slows my hairless down when taking it regularly... U should re up

[Jacob]

Old thread....thought I'd bump it up to see if anyone ever stuck with it and noticed anything...since the topic has come alive again in other forums :-"

[Jacob]

http://www.cocoscience.com/pdf/hair-soap.pdf

Cocoscience Premium Hair Soap is handmade using only safe and natural ingredients. Its potent formulation of Super Vitamin E Tocotrienols/Tocopherol complex, Full Spectrum Carotenoid complex, Premium ANH-Virgin Coconut Oil (VCO) and pure botanical essential oil ( Orange or Ylang-Ylang) works to keep your hair protected, nourished and clean without stripping it of its natural moisture. Carotenoid Complex are powerful anti-oxidants which neutralise harmful free radicals. It also enhances the appearance of dry damaged hair and heals scalp problem. Super Vitamin E is a natural full spectrum vitamin E complex that has been scientifically proven for its potency as a super anti-oxidant, anti-aging and cell-regenerative agent, while VCO protects, moisturizes and heals the skin and hair with its anti-viral, anti-fungal, anti-bacterial properties. Vitamin E works well for hair by promoting healthy blood flow in the scalp to reduce the appearance of greying hair. Cocoscience Premium Hair Soap is SLS-free and contains no synthetic colour, fragrance, preservative, animal extract and alcohol. It is effective for all skin types. Rinses clean with no soapy film.

They also have a "TRIENOL "Super Vitamin E" HAIR TREATMENT OIL "..have to find it yourself here as the url stays the same: http://www.cocoscience.com/

Natural ANH-VCO/MCT Oil with "Super Vitamin E" for healthy soft hair and scalp health. Safe, non-toxic and biodegradable. Simple to use.... just apply sparingly and massage into scalp to nourish and encourage hair growth. Spread thinly over hair to allow absorbtion of oil for strong soft and silky hairs. Wash off the oil with either shampoo or hair soap after about 30mins. Use weekly.

You can also use it as an everyday healthy hair oil instead of chemical-ladened hair cream... great for preventing scalp itch! The MCT components of C8, C10 & C12 offer excellent protection against virus, bacteria and fungal growth in the scalp thereby relieving scalp problems.

[Jacob]

80% Toco topical(although the ingreds list says 40% ): http://www.tricutis-kaufen.de/epages/62 ... 29-53-UE15

Ultraessence is a very concentrated Tocotrienol oil. Based on Tocomin, the Vitamin E concentrate with 80% Tocotrienols from virgin crude palm oil, it can be used for creating massage oils and skin care cremes or oils

Edit..they must mean Tocomin in the smaller % above..as this one says

Tocomin consists to 50% of pure Natural Vitamin E-Complex with predominately (80%) Tocotrienols, particularly the famous gamma-Tocotrienol. It is the preferred source of Tocotrienols for any applilcation

http://www.tricutis-kaufen.de/epages/62 ... -Tocomin30

"Decolored" version:http://www.tricutis-kaufen.de/epages/62 ... -Tocomin-C

Dr. Perricone vid on topical Tocos: http://www.dailyperricone.com/2009/06/d ... otrienols/