ok the recommended dose of Finasteride is 1 mg, but what I wanna know is; is .25 or .5 mg of finasteride just as effective as 1 mg? I have heard this theory before and just wanted it clarified.
Also, I'm gonna start taking half a pill of propecia to begin with as I dont wanna mess up my system too much to begin with and want to minimise the possibility of side effects. Can I theoretically go to taking a 1/5 a pill of proscar after 2 months on 1/2 a pill of propecia? Its all finasteride right? thanks.
Is 1/4 or 1/2 a pill of propecia just as effective as one?
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HairLossFight.com
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Hi Camino
Both Proscar's and Propecia's active ingredient is Finasteride. The pills are roughly the same size so perhaps there is more of some kind of a 'filler' substance in the Propecia pill.
I believe there is a study kicking around somewhere that shows Finasteride being effective in MPB even at doses of 0.2mg. I'll see if I can dig that study up for you.
Regards,
Sam
Both Proscar's and Propecia's active ingredient is Finasteride. The pills are roughly the same size so perhaps there is more of some kind of a 'filler' substance in the Propecia pill.
I believe there is a study kicking around somewhere that shows Finasteride being effective in MPB even at doses of 0.2mg. I'll see if I can dig that study up for you.
Regards,
Sam
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HairLossFight.com
- Site Admin
- Posts: 1218
- Joined: Sun Aug 24, 2003 3:24 am
- Hair Loss Type: Androgenetic Alopecia (Male Pattern Baldness)
- Norwood Level: Norwood III Vertex
- Have you had a hair transplant?: Yes
Camino, here is the dosage study that I was thinking of. It does state that 1mg of finasteride is the optimal dosage daily. HOWEVER 0.2mg was shown to have efficacy. You may want to consider this when deciding on your dosage (considering your level of hair loss)
Regards,
Sam
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J Am Acad Dermatol. 1999 Oct; 41(4): 555-63. Related Articles, Links
Clinical dose ranging studies with finasteride, a type 2 5alpha-reductase inhibitor, in men with male pattern hair loss.
Roberts JL, Fiedler V, Imperato-McGinley J, Whiting D, Olsen E, Shupack J, Stough D, DeVillez R, Rietschel R, Savin R, Bergfeld W, Swinehart J, Funicella T, Hordinsky M, Lowe N, Katz I, Lucky A, Drake L, Price VH, Weiss D, Whitmore E, Millikan L, Muller S, Gencheff C, et al.
Northwest Cutaneous Research Specialists, Portland, Oregan, USA.
BACKGROUND: Androgenetic alopecia is a common condition of adult men. Finasteride, a type 2 5alpha-reductase inhibitor, decreases the formation of dihydrotestosterone from testosterone. OBJECTIVE: Two separate clinical studies were conducted to establish the optimal dose of finasteride in men with this condition. METHODS: Men from 18 to 36 years of age with moderate vertex male pattern hair loss received finasteride 5, 1, 0.2, or 0.01 mg/day or placebo based on random assignment. Efficacy was determined by scalp hair counts, patient self-assessment, investigator assessment, and assessment of clinical photographs. Safety was assessed by clinical and laboratory measurements and by analysis of adverse experiences. RESULTS: Efficacy was demonstrated for all end points for finasteride at doses of 0.2 mg/day or higher, with 1 and 5 mg demonstrating similar efficacy that was superior to lower doses. Efficacy of the 0.01 mg dose was similar to placebo. No significant safety issues were identified in the trials. CONCLUSION: Finasteride 1 mg/day is the optimal dose for the treatment of men with male pattern hair loss and was subsequently identified for further clinical development.
Regards,
Sam
----
J Am Acad Dermatol. 1999 Oct; 41(4): 555-63. Related Articles, Links
Clinical dose ranging studies with finasteride, a type 2 5alpha-reductase inhibitor, in men with male pattern hair loss.
Roberts JL, Fiedler V, Imperato-McGinley J, Whiting D, Olsen E, Shupack J, Stough D, DeVillez R, Rietschel R, Savin R, Bergfeld W, Swinehart J, Funicella T, Hordinsky M, Lowe N, Katz I, Lucky A, Drake L, Price VH, Weiss D, Whitmore E, Millikan L, Muller S, Gencheff C, et al.
Northwest Cutaneous Research Specialists, Portland, Oregan, USA.
BACKGROUND: Androgenetic alopecia is a common condition of adult men. Finasteride, a type 2 5alpha-reductase inhibitor, decreases the formation of dihydrotestosterone from testosterone. OBJECTIVE: Two separate clinical studies were conducted to establish the optimal dose of finasteride in men with this condition. METHODS: Men from 18 to 36 years of age with moderate vertex male pattern hair loss received finasteride 5, 1, 0.2, or 0.01 mg/day or placebo based on random assignment. Efficacy was determined by scalp hair counts, patient self-assessment, investigator assessment, and assessment of clinical photographs. Safety was assessed by clinical and laboratory measurements and by analysis of adverse experiences. RESULTS: Efficacy was demonstrated for all end points for finasteride at doses of 0.2 mg/day or higher, with 1 and 5 mg demonstrating similar efficacy that was superior to lower doses. Efficacy of the 0.01 mg dose was similar to placebo. No significant safety issues were identified in the trials. CONCLUSION: Finasteride 1 mg/day is the optimal dose for the treatment of men with male pattern hair loss and was subsequently identified for further clinical development.
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